Biomarkers of renal (serum creatinine) and hepatic dysfunction (AST, ALT) were higher in blood Group A or AB patients. Their investigation found a higher proportion of COVID-19 patients with blood group A or AB required mechanical ventilation and continuous renal replacement therapy (CRRT) and had a longer intensive care unit (ICU) stay (13.5 days) compared with patients with blood group O or B. This was a multicenter retrospective analysis and prospective observational sub-study of critical care patients (n = 95). (2020) evaluated whether ABO blood groups are associated with different severities of COVID-19. The first investigation led by Hoiland et al. Two recent studies were published this month (October 2020) in the journal Blood Advances supporting the theory that individuals with blood type O are at a lower risk for contracting COVID-19 and severe coronavirus illness. This study had several limitations in that the sample size was small and the control population lacked information on subject age, sex and chronic medical conditions, preventing a proper analysis to adjust for these factors. Their research showed blood group A individuals had a higher risk for COVID-19 and blood group O was associated with a lower risk for the infection compared with non-O blood groups. (2020) evaluated 2,173 patients and found the ABO blood group to be a biomarker for COVID-19 susceptibility. Additional studies found patients with blood group O have reduced levels of factor VIII and von Wilebrand factor, potential determinants which may provide a protective effect against vascular abnormalities in the pulmonary system (Hoiland et al., 2020).Ī study conducted in the earlier days of the SARS-CoV-2 pandemic by Zhao et al. SARS-CoV-2 also binds to ACE2 and therefore, may also be affected by the anti-A antibody. Research conducted on the first severe acute respiratory syndrome coronavirus-1 (SARS-CoV-1) found the anti-A antibody in people with blood group O or B may block the interaction between the virus and the receptor for angiotensin converting enzyme 2 (ACE2) found in cells, a mechanism for virus transmission (Guillon et al., 2008). *Reference: WebMd, 2020 Blood Type Linked to COVID-19? For nurses, knowing your patient’s blood type is critical when administering blood products to prevent lethal transfusion reactions. Combining these components results in eight common blood types: A+, A-, B+, B-, O+, O-, AB+, AB. In addition to the A and B antigens and antibodies, there is a protein called the Rh factor, which can be present (+) or absent (-). Your blood type is determined by the presence or absence of specific antigens (A and B) on the surface of the red blood cells and antibodies (A and B) in the plasma (American Red Cross, 2020). Should we be concerned about these new findings?įirst, let’s review the blood type basics. But is this a hidden risk factor for coronavirus disease 2019 (COVID-19)? Recent reports have added to the hypothesis that blood type is linked to COVID-19. Facing Ethical Challenges with Strength and Compassionīe positive! That’s my motto and also my blood type.
BEING A BLOOD TYP O PROFESSIONAL
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